Here are key words and phrases for Acetyl-L-Carnitine (ALCAR) based on your detailed document:


🔬 Scientific / Biochemical Terms

  • Acetyl-L-Carnitine (ALC / ALCAR)

  • L-Carnitine

  • Acetyl-CoA

  • Mitochondria

  • Energy metabolism

  • Neurotransmitter synthesis (Acetylcholine)

  • Beta-acetoxy-gamma-N, N, N-trimethylaminobutyrate

  • Antioxidant

  • Neuroprotective

  • Anti-apoptotic

  • Bioavailable


🧠 Cognitive & Neurological Benefits

  • Mental performance

  • Memory enhancement

  • Cognitive function

  • Mental stamina

  • Focus & alertness

  • Mild mood enhancement

  • Brain function support

  • Alzheimer’s support

  • ADHD (fragile X syndrome)

  • Senile brain function

  • Multiple sclerosis fatigue


💪 Physical / Cellular Benefits

  • Energy production

  • Muscle movement

  • Fatty acid transport

  • ATP generation

  • Chronic fatigue support

  • Diabetic neuropathy

  • Chemotherapy-induced neuropathy

  • Sperm motility and volume

  • Erectile dysfunction

  • Anti-aging / longevity

  • Cardiovascular support


🧬 Conditions & Therapeutic Uses

  • Alzheimer’s disease

  • ADHD (fragile X)

  • Chronic fatigue syndrome

  • Diabetic neuropathy

  • Erectile dysfunction

  • Male infertility

  • Peyronie’s disease

  • Insulin resistance

  • Hypertension

  • Multiple sclerosis

  • Age-related testosterone deficiency

  • Depression in elderly


💊 Dosage & Supplementation

  • 1500–4000 mg daily

  • Divided doses

  • Combined with L-Carnitine or Propionyl-L-Carnitine

  • With or without Alpha Lipoic Acid

  • Vegetarian deficiency risk

  • Found in red meat (mutton highest)


⚠️ Precautions & Side Effects

  • Nausea

  • Restlessness

  • Insomnia (high doses)

  • Take with food to reduce nausea

  • Monitor thyroid, hormone, and medication interactions

  • Start with low doses (e.g., 300 mg)



 
Research Studies / References
arw ^ Steiber A, Kerner J, Hoppel C (2004). "Carnitine: a nutritional, biosynthetic, and functional perspective". Mol. Aspects Med. 25 (5-6): 455-73.
doi:10.1016/j.mam.2004.06.006. PMID 15363636.
   
arw ^ A. J. Liedtke, S. H. Nellis, L. F. Whitesell and C. Q. Mahar (1 November 1982). "Metabolic and mechanical effects using L- and D-carnitine in working swine hearts". Heart and Circulatory Physiology 243 (5): H691-H697. PMID 7137362. http://ajpheart.physiology.org/cgi/content/abstract/243/5/H691.
   
arw ^ "L-Carnitine". Archived from the original on 2007-05-08. http://web.archive.org/web/20070508224849/http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/lca_0060.shtml.
Retrieved 2007-06-01.
   
arw ^ Cederblad, G; Niklasson, A; Rydgren, B; Albertsson-Wikland, K; Olegård, R; "Carnitine in Maternal and Neonatal Plasma"; Acta Pædiatrica; Published Online: 21 Jan 2008; Volume 74, Issue 4: Pp 500 - 504
   
arw ^ Cederblad, G; Fahraeus, L; Lindgren, K; "Plasma carnitine and renal-carnitine clearance during pregnancy"; American Journal of Clinical Nutrition; 1986; Volume 44:Pp
   
arw

^ Olpin S (2005). "Fatty acid oxidation defects as a cause of neuromyopathic disease in infants and adults". Clin. Lab. 51 (5-6): 289-306. PMID 15991803.

   
arw ^ Claudio Cavazza, Composition for the Prevention and Treatment of Osteoporosis due to Menopause Syndrome (2002), US Patent 6,335,038, column 4.
   
arw ^ Claudio Cavazza, Composition for the Prevention and Treatment of Osteoporosis due to Menopause Syndrome (2002), US Patent 6,335,038, columns 3-4.
   
arw ^ Claudio Cavazza, Composition for the Prevention and Treatment of Osteoporosis due to Menopause Syndrome (2002), US Patent 6,335,038, column 3.
   
arw ^ Cacciatore L, Cerio R, Ciarimboli M, Cocozza M, Coto V, D'Alessandro A, D'Alessandro L, Grattarola G, Imparato L, Lingetti M (1991). "The therapeutic effect of L-carnitine in patients with exercise-induced stable angina: a controlled study.". Drugs Exp Clin Res 17 (4): 225-235. PMID 1794297.
   
arw ^ Bartels GL, Remme WJ, Pillay M, et al. (July 1994). "Effects of L-propionylcarnitine on ischemia-induced myocardial dysfunction in men with angina pectoris". The American Journal of Cardiology 74 (2): 125-130. doi:10.1016/0002-9149(94)90084-1. PMID 8023775.
   
arw ^ Michael A. Arsenian (November - December 1997). "Carnitine and its derivatives in cardiovascular disease". Progress in Cardiovascular Diseases 40 (3): 265-286. doi:10.1016/S0033-0620(97)80037-0. PMID 9406679.
   
arw ^ Kamyar Kalantar-Zadeh, MPHa, Stefan D. Anker, Tamara B. Horwich and Gregg C. Fonarow (June 2008). "Nutritional and Anti-Inflammatory Interventions in Chronic Heart Failure". The American Journal of Cardiology 101 (11): S89-S103. doi:10.1016/j.amjcard.2008.03.007. PMID 18514634.
   
arw ^ Geltrude Mingrone, Aldo V. Greco, Esmeralda Capristo, Giuseppe Benedetti, Annalisa Giancaterini, Andrea De Gaetano, and Giovanni Gasbarrini (1 February 1999). "L-Carnitine Improves Glucose Disposal in Type 2 Diabetic Patients". Journal of the American College of Nutrition 18 (1): 77-82. PMID 10067662. http://www.jacn.org/cgi/content/full/18/1/77.
   
arw ^ Wei Huang, Sobia N. Shaikh, Malliga E. Ganapathy, Ullrich Hopfer, Frederick H. Leibach, A. Lee Carter and Vadivel Ganapathy (October 1999). "Carnitine transport and its inhibition by sulfonylureas in human kidney proximal tubular epithelial cells". Biochemical Pharmacology 58 (8): 1361-1370. doi:10.1016/S0006-2952(99)00219-1. PMID 10487540.
   
arw ^ Lenzi A, Lombardo F, Sgro P, Salacone P, Caponecchia L, Dondero F, Gandini L (2003). "Use of carnitine therapy in selected cases of male factor infertility: a double-blind crossover trial.". Fertility and Sterility (2003), Volume 79 , Issue 2 , Pages 292 - 300 79 (2): 292-300. PMID 12568837.
   
arw ^ Seo JT, Kim KT, Moon MH, Kim WT (April 2010). "The significance of microsurgical varicocelectomy in the treatment of subclinical varicocele". Fertil. Steril. 93 (6): 1907-10. doi:10.1016/j.fertnstert.2008.12.118. PMID 19249033.
   
arw ^ "University of Maryland Medical Centre, April 2002". http://www.umm.edu/altmed/articles/carnitine-l-000291.htm. Retrieved 2008-05-20.
   
arw ^ Mariano Malaguarnera, Lisa Cammalleri, Maria Pia Gargante, Marco Vacante, Valentina Colonna and Massimo Motta: "L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial", American Journal of Clinical Nutrition, Volume 86, No. 6, 1738-1744, December 2007
   
arw ^ "Toxicity, Valproate: Treatment & Medication". http://emedicine.medscape.com/article/819315-treatment.
   
arw ^ Linus Pauling Institute at Oregon State University
   
arw ^ http://www.encyclopedia.com/doc/1G1-131086133.html
   
arw ^ "NHPD Monthly Communique, Vol. 1, Issue 1, September 2005". http://www.hc-sc.gc.ca/dhp-mps/prodnatur/bulletins/_communiques/communique_sep05-eng.php. Retrieved 2007-06-01.[dead link]
 
 

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